EGFR (phospho Tyr1086) antibody (HL3284)

Clone Name: HL3284

Light Chain: Kappa

Application Note: WB: 1:5000-1:20000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Specificity/Sensitivity: The full-length EGFR includes the 24 aa signal peptide that is cleaved during EGFR maturation. The Tyr1086 of mature EGFR is equivalent to Tyr1110 of uncleaved EGFR.

Form: Liquid

Buffer (with preservative): PBS, no Preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]

Uniprot ID: P00533

Antigen Species: Human

Immunogen: Carrier-protein conjugated synthetic peptide surrounding phospho Tyr1086 of human EGFR. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: epidermal growth factor receptor

• Artikelnummer: GTX640938-S-25
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX640938-S-25
• Verpackungseinheit: 25 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 1956
• Wirt: Rabbit
• Konjugat: Unconjugated