Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: [(1R,3aR,4S,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2,6-dimethoxy-4,1-phenylene)bis-ß-D-glucopyranoside
Purity: ≥95%
Formula Markup: C34H46O18
Formula Weight: 742.71824
CAS Number: 39432-56-9
Notes: Eleutheroside E is a glycoside and major component of E. senticosus and has diverse biological activities.{46673} It protects against axonal and dendritic atrophies induced by amyloid-β (25-35) (Aβ (25-35); Item No. 24155) in primary rat cortical neurons.{46673,46675,46674,46676} Eleutheroside E (15, 30, and 60 mg/kg) reduces macrophage infiltration, pannus formation, cartilage damage, bone erosion, and the production of TNF-α and IL-6 in a mouse model of collagen-induced arthritis.{46675} It increases insulin sensitivity and reduces pancreatic α- and β-cell death in db/db diabetic mice.{46674} Eleutheroside E (10 and 50 mg/kg) increases the latency to enter the dark chamber in a passive avoidance test and the levels of glutathione (GSH) in the hippocampus and decreases errors in the Y-maze test and hippocampal malondialdehyde (MDA) levels in a mouse model of sleep deprivation-induced stress.{46676}
Deutsch
English
