Enoximone, CAS 77671-31-9

Shelf life (days): 730.0

Formulation: A solid

Formal Name: 1,3-dihydro-4-methyl-5-[4-(methylthio)benzoyl]-2H-imidazol-2-one

Purity: ≥98%

Formula Markup: C12H12N2O2S

Formula Weight: 248.30196

CAS Number: 77671-31-9

Notes: Enoximone is a phosphodiesterase 3 (PDE3) inhibitor (IC50 = 5.9 µM).{56134} It is selective for PDE3 over PDE1, -2, and -4 (IC50s = 2,100, 2,900, and 21.1 µM, respectively). Enoximone increases the force of contraction and cAMP levels in isolated canine right ventricular trabeculae, an effect that can be reversed by carbamoylcholine (carbachol; Item No. 14486).{56135} In vivo, enoximone (0.1-1 mg/kg) increases cardiac contractile force in dogs.{56136} Formulations containing enoximone have been used in the treatment of congestive heart failure.

• Artikelnummer: CAY30868-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 30868-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK