Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 1-cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Purity: ≥98%
Formula Markup: C19H22FN3O3
Formula Weight: 359.4
CAS Number: 93106-60-6
Notes: Enrofloxacin is a fluoroquinolone antibiotic.{54914} It is active against panels of Campylobacter, E. coli, and Salmonella isolates (mean MIC50s = 0.06, 0.5, and 0.03 µg/ml, respectively). It is also active against equine isolates of L. intracellularis (MICs = 0.125-0.5 µg/ml).{54915} Enrofloxacin inhibits bacterial DNA gyrase.{54916} In vivo, enrofloxacin (10 mg/kg) increases survival in a mouse model of enteropathogenic E. coli-induced sepsis. Formulations containing enrofloxacin have been used in the treatment of veterinary bacterial infections.