Epothilone A, CAS 152044-53-6

Product Description: Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.

Applications: Cancer-programmed cell death

Formula: C26H39NO6S

References: [1]Kowalski RJ, et al. Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)). J Biol Chem. 1997 Jan 24;272(4):2534-41./[2]Cheng KL, et al. Novel microtubule-targeting agents - the epothilones. Biologics. 2008 Dec;2(4):789-811.

CAS Number: 152044-53-6

Molecular Weight: 493.66

Compound Purity: 99.75

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Apoptosis;Microtubule/Tubulin

• Artikelnummer: MEXHY-13503-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-13503-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK