Shelf life (days): 1460.0
Formulation: A solid
Formal Name: (2S)-2-(3,4-dihydroxyphenyl)-7-(ß-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C21H22O11
Formula Weight: 450.4
CAS Number: 38965-51-4
Notes: Eriodictyol 7-O-glucoside is a flavanone glucoside that has been found in V. coloratum and has diverse biological activities.{68054,68055,68056} It scavenges hydroxyl and superoxide anion radicals in cell-free assays (IC50s = 0.28 and 0.3 mM, respectively).{68054} Eriodictyol 7-O-glucoside activates nuclear factor E2-related factor 2 (Nrf2) in a reporter assay.{68055} It protects against cytotoxicity induced by cisplatin (Item No. 13119) in human renal mesangial cells (HRMCs), but not A549 lung or MDA-MB-231 breast cancer cells, when used at a concentration of 80 µM. Eriodictyol 7-O-glucoside (30 mg/kg) attenuates neurological deficits and reduces infarct volume in a rat model of cerebral ischemia induced by middle cerebral artery occlusion (MCAO).{68056}
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