Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), CF740 conjugate, 0.1mg/mL

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), CF740 conjugate, 0.1mg/mL
Artikelnummer
BTMBNC742299-500
Verpackungseinheit
500 uL
Hersteller
Biotium

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Description: This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)

Conjugate: CF740

Concentration: 0.1 mg/mL

Storage buffer: PBS, 0.1% rBSA, 0.05% azide

Clone: ESR1/2299R

Immunogen: Recombinant full-length human Estrogen Receptor alpha protein

Antibody Reactivity: Estrogen Receptor, alpha

Entrez Gene ID: 2099

Z-Antibody Applications: IHC, FFPE (verified)/WB (verified)

Verified AB Applications: IHC (FFPE) (verified)/WB (verified)

Antibody Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody/Immunohistology (formalin): 1-2 ug/mL for 30 minutes at RT/Western Blot 0.5-2 ug/mL/Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes/Optimal dilution for a specific application should be determined by user
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Artikelnummer BTMBNC742299-500
Hersteller Biotium
Hersteller Artikelnummer BNC742299-500
Verpackungseinheit 500 uL
Mengeneinheit STK
Reaktivität Human
Klonalität Recombinant
Methode Western Blotting, Immunohistochemistry
Isotyp IgG
Wirt Rabbit
Konjugat Conjugated, CF740
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