Clone Name: 6A12
Light Chain: Kappa
Application Note: WB: 1 - 5 μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 59
Positive Control: Myc-DDK-tagged ESR2-transfected 293T , Recombinant fusion protein
Form: Liquid
Buffer (with preservative): PBS, no Preservative.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008]
Uniprot ID: Q92731
Antigen Species: Human
Immunogen: Amino acids 1-153 of human ER-§ expressed in E. coli.
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: estrogen receptor 2
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