Shelf life (days): 1460.0
Formulation: A neat oil
Formal Name: 1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane
Purity: ≥98%
Formula Markup: C10H18O
Formula Weight: 154.3
CAS Number: 470-82-6
Notes: Eucalyptol is a bicyclic monoterpene that has been found in Eucalyptus and other plants, including C. sativa and has diverse biological activities, including anti-inflammatory, decongestant, antinociceptive, and insect repellent properties.{21071,39875,39876,39877,39878} Eucalyptol (10 μM) inhibits TNF-α, IL-1β, IL-4, and IL-5 production by primary human lymphocytes stimulated by ionomycin (Item No. 10004974) and phorbol 12-myristate 13-acetate (PMA; Item No. 10008014).{39875} It also decreases LPS-induced mucus production by primary human nasal turbinate slices when used at a concentration of 10 μM.{39876} Eucalyptol (400 mg/kg) decreases carrageenan-induced hind paw edema in rats and reduces the time spent licking the hind paw in a formalin-induced nociception test in mice.{39877} It inhibits A. aegypti mosquitoes from feeding on anesthetized gerbils when applied topically at a concentration of 10% and from laying eggs in an ovipositional bioassay when used at a concentration of 1% in standing water.{39878} Formulations containing eucalyptol have been used in mouthwash and cough suppressants.