Clone Name: IM20
Light Chain: Kappa
Application Note: WB: 1:100–1:200. IHC-P: 1:200–1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 55
Form: Liquid
Buffer (with preservative): Tissue culture supernatant, 0.09% Sodium azide.
Concentration:
Background: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Uniprot ID: Q16658
Antigen Species: Human
Immunogen: Prokaryotic recombinant protein corresponding to the C-terminal region of the fascin molecule.
Purification: Unpurified
Conjugation: Unconjugated
Full Name: fascin actin-bundling protein 1
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