Product Description: FAUC 213 is an orally active and highly selective dopamine D4 receptor complete antagonist with a Ki of 2.2 nM for hD4.4. FAUC 213 has less activity on D2 and D3 receptors (Kis of 3.4 μM, 5.3 μM for hD2, hD3, respectively). FAUC 213 can cross the blood-brain barrier (BBB). FAUC 213 exhibits atypical antipsychotic characteristic[1].
Applications: Neuroscience-Neuromodulation
Formula: C18H19ClN4
References: [1]Frank Boeckler, et al. FAUC 213, a highly selective dopamine D4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia. Psychopharmacology (Berl). 2004 Aug;175(1):7-17.
CAS Number: 337972-47-1
Molecular Weight: 326.82
Compound Purity: 99.86
Research Area: Neurological Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Dopamine Receptor
Deutsch
English
