Ferroptosis Inhibitor D1

Shelf life (days): 730.0

Formulation: A crystalline solid

Formal Name: N1-cyclohexyl-5-(2-methyl-2H-tetrazol-5-yl)benzene-1,2-diamine

Purity: ≥98%

Formula Markup: C14H20N6

Formula Weight: 272.4

Notes: Ferroptosis inhibitor D1 is a free radical scavenger and an inhibitor of ferroptosis.{68885} It scavenges 41.27% of DPPH (Item No. 14805) radicals in a cell-free assay when used at a concentration of 0.4 µM. Ferroptosis inhibitor D1 (0.5 µM) inhibits lipid peroxidation induced by the ferroptosis inducer erastin (Item No. 17754) in HT-1080 cells and inhibits erastin-induced ferroptosis in the same cells (IC50 = 22 nM). In vivo, ferroptosis inhibitor D1 (5 mg/kg) reduces infarct volume and improves neurological deficits in a mouse model of ischemic brain injury induced by transient middle cerebral artery occlusion (MCAO).

• Artikelnummer: CAY41822-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41822-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK