Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic-1,2-13C2 acid-13C
Purity: ≥98%
Formula Markup: C11[13C]3H12FNO3
Formula Weight: 264.2
CAS Number: 1185049-09-5
Notes: Flumequine-13C3 is intended for use as an internal standard for the quantification of flumequine (Item No. 21645) by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.{58787} It is active against S. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, and K. pneumoniae (MICs = 1-100 µg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 µg/ml).{58788} It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.{34277} In vivo, flumequine (50 mg/kg) increases survival in rat models of P. vulgaris-induced urinary tract infection and P. mirabilis-induced prostatitis.{58787} Formulations containing flumequine have been used in the treatment of urinary tract infections in veterinary medicine.
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