Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 9-fluoro-11ß,17-dihydroxy-6a-methyl-pregna-1,4-diene-3,20-dione
Purity: ≥98%
Formula Markup: C22H29FO4
Formula Weight: 376.5
CAS Number: 426-13-1
Notes: Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM; Kd = 2.8 nM in a radioligand binding assay).{36308,36309} Fluorometholone (0.01%) decreases survival of cultured corneal epithelial cells and inhibits their migration in a scratch assay following 12 hours of treatment.{36311} Formulations containing fluorometholone have been used for the treatment of eye inflammation.