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Anti-CD123 Antibody, FITC-Labeled
Anti-CD123 Antibody, FITC-Labeled
Artikelnummer
BPS101955-1
Verpackungseinheit
25 µg
Hersteller
BPS Bioscience
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Products from BPS Bioscience require a minimum order value above 400€
Applications: Useful for studying expression of CD123 on the cell surface by flow cytometry.
Assay Conditions: One million CD123 CHO cells (BPS Bioscience #79640-H) were blocked and stained with 1 µg of anti-CD123 antibody, FITC-labeled (BPS Bioscience #101955) for 30 minutes on ice, washed three times, and analyzed by flow cytometry. CD123 CHO cells (green) were compared to parental CHO-K1 cells (blue). Y-axis represents the cell count, while X-axis shows FITC intensity.
Background: CD123, also known as interleukin 3 receptor alpha (IL3Ra), is a transmembrane protein found in pluripotent progenitor cells and involved in hematopoietic lineage differentiation. It can also be found in basophils, plasmacytoid dendritic cells and dendritic cells. CD123 is overexpressed on leukemic hematopoietic stem cells (HSCs), but not normal HSCs. It has been found in acute myeloid and B-lymphoid leukemias, blastic plasmacytoid dendritic neoplasms (BPDCN) and hairy cell leukemia. This expression profile makes CD123 an attractive target in cancer therapy. CAR-Ts and other therapies targeting CD123 are currently being evaluated in clinical trials.
Cross Reactivity: This antibody recognizes human CD123. It has not been tested on other species.
Description: This anti-CD123 antibody is a human purified recombinant antibody, which is labeled with fluorescein isothiocyanate (FITC). This antibody has been tested by flow cytometry for binding to human CD123 on the surface of CD123 CHO Recombinant Cells (BPS Bioscience #79640-H).
Format: Aqueous buffer solution.
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 0.09% Sodium Azide, 0.2% BSA, and up to 20% glycerol. May contain a protein stabilizer.
Host Cell Line: HEK293
Purification: Protein A affinity chromatography from HEK293 supernatant.
Purity: ≥90%
Storage Stability: At least 6 months at 4°C. Protect from prolonged exposure to light. DO NOT FREEZE. The antibody solution should be stored undiluted between 2°C and 8°C.
Uniprot: O75794
Warnings: Avoid freeze/thaw cycles
Biosafety Level: Not applicable (BSL-1)
Applications: Useful for studying expression of CD123 on the cell surface by flow cytometry.
Assay Conditions: One million CD123 CHO cells (BPS Bioscience #79640-H) were blocked and stained with 1 µg of anti-CD123 antibody, FITC-labeled (BPS Bioscience #101955) for 30 minutes on ice, washed three times, and analyzed by flow cytometry. CD123 CHO cells (green) were compared to parental CHO-K1 cells (blue). Y-axis represents the cell count, while X-axis shows FITC intensity.
Background: CD123, also known as interleukin 3 receptor alpha (IL3Ra), is a transmembrane protein found in pluripotent progenitor cells and involved in hematopoietic lineage differentiation. It can also be found in basophils, plasmacytoid dendritic cells and dendritic cells. CD123 is overexpressed on leukemic hematopoietic stem cells (HSCs), but not normal HSCs. It has been found in acute myeloid and B-lymphoid leukemias, blastic plasmacytoid dendritic neoplasms (BPDCN) and hairy cell leukemia. This expression profile makes CD123 an attractive target in cancer therapy. CAR-Ts and other therapies targeting CD123 are currently being evaluated in clinical trials.
Cross Reactivity: This antibody recognizes human CD123. It has not been tested on other species.
Description: This anti-CD123 antibody is a human purified recombinant antibody, which is labeled with fluorescein isothiocyanate (FITC). This antibody has been tested by flow cytometry for binding to human CD123 on the surface of CD123 CHO Recombinant Cells (BPS Bioscience #79640-H).
Format: Aqueous buffer solution.
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 0.09% Sodium Azide, 0.2% BSA, and up to 20% glycerol. May contain a protein stabilizer.
Host Cell Line: HEK293
Purification: Protein A affinity chromatography from HEK293 supernatant.
Purity: ≥90%
Storage Stability: At least 6 months at 4°C. Protect from prolonged exposure to light. DO NOT FREEZE. The antibody solution should be stored undiluted between 2°C and 8°C.
Uniprot: O75794
Warnings: Avoid freeze/thaw cycles
Biosafety Level: Not applicable (BSL-1)
| Artikelnummer | BPS101955-1 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 101955-1 |
| Green Labware | Nein |
| Verpackungseinheit | 25 µg |
| Mengeneinheit | STK |
| Klonalität | Monoclonal |
| Isotyp | IgG1 |
| Wirt | Human |
| Produktinformation (PDF) |
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| MSDS (PDF) |
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