Cetuximab, CAS 205923-56-4

Product Description: Cetuximab (C225) is a human IgG1 monoclonal antibody that inhibits epidermal growth factor receptor (EGFR), with a Kd of 0.201 nM for EGFR by SPR. Cetuximab has potent antitumor activity[1].

Applications: Cancer-Kinase/protease

Formula: N/A

References: [1]Goldstein NI, et al. Biological efficacy of a chimeric antibody to the epidermal growth factor receptor in a human tumor xenograft model. Clin Cancer Res. 1995 Nov;1(11):1311-8./[2]Gustafsson H, et al. EPR Oximetry of Cetuximab-Treated Head-and-Neck Tumours in a Mouse Model. Cell Biochem Biophys. 2017 Jul 29./[3]Huang SM, et al. Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. Cancer Res. 1999 Apr 15;59(8):1935-40.

CAS Number: 205923-56-4

Molecular Weight: 145543.35

Compound Purity: 99.70

Research Area: Cancer

Solubility: H2O

Target: EGFR

• Artikelnummer: MEXHY-P9905-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P9905-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK