DEDN6526A

Product Description: DEDN6526A is an antibody-drug conjugate (ADC) consisting of the humanized anti-ETBR antibody DEDN6526A (RG-7636) (HY-P990573 conjugated with valine-citrulline (vc) and the tubulin inhibitor MMAE (McMMAF) (HY-15575). DEDN6526A induces apoptosis and can be used in melanoma research[1].

Formula: N/A

References: [1]Sandhu S, et al. Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma. Invest New Drugs. 2020 Jun;38(3):844-854.

Molecular Weight: N/A

Research Area: Cancer

Target: Antibody-Drug Conjugates (ADCs);Apoptosis;Endothelin Receptor;Microtubule/Tubulin

• Artikelnummer: MEXHY-171734-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-171734-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK