Target Synonym: ERK;MAPK1/MAPK;MAPK;MAPK1/MAPK3;ERK2;PRKM1;PRKM2;MAPK1;ERK 2;ERK-2;ERT1;Extracellular Signal Regulated Kinase 2;Extracellular signal-regulated kinase 2;MAP kinase 1;MAP kinase 2;MAP kinase isoform p42;MAPK 1;MAPK 2;MAPK2;mitogen-activated;mitogen-activated protein kinase 1;Mitogen-activated protein kinase 2;MK01;p38;p40;p41;p41mapk;P42MAPK;p42-MAPK;protein kinase;protein tyrosine kinase ERK2
Background: MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
Immunogen: Recombinant Human ERK2/MAPK1/MAPK2 Protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:2000
Calculated MW: 40 kDa
Observed MW: 40 kDa