Target Synonym: Intercellular Adhesion Molecule;ICAM2;CD102;ICAM-2;Intercellular Adhesion Molecule 2
Background: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Immunogen: Recombinant Human ICAM-2/CD102 protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:50-1:200