PARP/PARP1 Monoclonal Antibody

Target Synonym: SCA;ARTD;Poly[ADP-ribose] synthase;Poly ADP ribose polymerase;poly(ADP-ribose) polymerase;Poly [ADP-ribose] polymerase;NAD(+) ADP-ribosyltransferase;ADP-ribosyltransferase diphtheria toxin-like;pADPRT;ADPRT;ADPRT 1;ADPRT1;ARTD1;PARP;PARP-1;PPOL;pADPRT-1;PARP1;Cleaved PARP;ADP-ribosyltransferase diphtheria toxin-like 1;APOPAIN;NAD(+) ADP-ribosyltransferase 1;Poly [ADP-ribose] polymerase 1;Poly ADP ribose polymerase 1;poly(ADP-ribose) polymerase 1;Poly[ADP-ribose] synthase 1;SCA1;ADPRT;ADPRT 1;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;poly(ADP-ribose) polymerase 1;PPOL

Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Immunogen: E. coli-derived Human PARP/PARP1 fragment

Buffer: 0.2 μm filtered solution in PBS

Dilution: IHC-P 1:200-1:2000

• Artikelnummer: ELSAN200247P-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: AN200247P-100
• Verpackungseinheit: 100μL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG2a
• Wirt: Mouse
• Konjugat: Unconjugated