PE Anti-Human CD22 Antibody(HIB22), Mouse, Monoclonal

Clone No.: HIB22.

Swissprot: P20273.

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Conjugation: PE.

Background: CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

• Artikelnummer: ELSE-AB-F1321D-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: E-AB-F1321D-100
• Verpackungseinheit: 100 Tests
• Mengeneinheit: PAK
• Reaktivität: Human
• Methode: Flow Cytometry
• Isotyp: Mouse IgG1 κ
• Human Gene ID: 933
• Wirt: Mouse