Product Description: PF-08046054 (SGN-PDL1V) is a PD-L1-directed antibody-drug conjugate (ADC), which is comprised of an anti-PD-L1 antibody conjugated to the vedotin drug-linker, VcMMAE (HY-15575). PF-08046054 is direct cytotoxicity to PD-L1-expressing tumor cells via the intracellular delivery of MMAE. PF-08046054 can be used for the study of solid tumors[1].
Formula: N/A
References: [1]Byron Kwan, et al. 783 SGN-PDL1V, a novel, investigational PD-L1-directed antibody-drug conjugate for the treatment of solid tumors Free. Regular and Young Investigator Award Abstracts. Immuno-Conjugates and Chimeric Molecules.
Molecular Weight: N/A
Research Area: Cancer
Target: Antibody-Drug Conjugates (ADCs);Microtubule/Tubulin;PD-1/PD-L1