Anti-Mouse CD8a (53-6.7) In Vivo Antibody - Ultra-Low Endotoxin

Anti-Mouse CD8a (53-6.7) In Vivo Antibody - Ultra-Low Endotoxin, Host: Rat, Rat IgG2a Kappa
Artikelnummer
ICH1044UL-5MG
Verpackungseinheit
5mg
Hersteller
Ichorbio

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Target: CD8a

Clone: 53-6.7

Specificity: Anti-CD8a In Vivo Antibody - Ultra Low Endotoxin (53-6.7) recognizes Lyt 2, lymphocyte differentiation antigen. The antibody precipitates 44 kDa and 33 kDa proteins and reacts with non-polymorphic determinant.

Purification method: This monoclonal antibody was purified using Protein G

Antigen Distribution: Present on the surface of most thymocytes and a subpopulation of mature T-lymphocytes which include most T suppressor/cytotoxic cells. CD8 participates in T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase lck.

Background: CD8, a.k.a Lyt-2, Ly-2, or T8, consists of disulfide-linked A and β chains that form the A(CD8a)/β(CD8b) heterodimer and A/A homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 A/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR A/β T cells.

Immunogen: Mouse thymus or spleen

Concentration: 1.0 - 5.0 mg/ml

Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Purity: >98% by SDS-PAGE and HPLC

Endotoxin: ≤ 0.5 EU/mg as determined by the LAL method

Aggregation: Aggregation level ≤ 1%

Use: Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Mehr Informationen
Artikelnummer ICH1044UL-5MG
Hersteller Ichorbio
Hersteller Artikelnummer ICH1044UL-5MG
Verpackungseinheit 5mg
Mengeneinheit STK
Reaktivität Mouse (Murine)
Klonalität Monoclonal
Methode Immunohistochemistry (frozen), Immunoprecipitation, Western Blotting, Flow Cytometry, Cytometry by time of flight (CyTOF)
Isotyp Rat IgG2a kappa
Wirt Rat
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