Target Synonym: LymphocyteantigenT1/Leu;Lymphocyte antigen T1/Leu;T-cellsurfaceglycoproteinCD;T-cell surface glycoprotein CD;OTTHUMP;LEU;CD5;LEU1;T1;CD 5;CD5 antigen;CD5 antigen (p56 62);CD5 molecule;Leu-1;Ly-1;LyA;LymphocyteantigenT1/Leu-1;OTTHUMP00000236973;T-cellsurfaceglycoproteinCD5;Tp67;T-cell surface glycoprotein CD5;Lymphocyte antigen T1/Leu-1;Tp67;Leu-1;Ly-1;CD 5;CD5;CD5 antigen (p56 62);CD5 antigen;CD5 molecule;CD5;LEU1;LyA;Lymphocyte antigen T1/Leu-1;OTTHUMP00000236973;T-cell surface glycoprotein CD5;T1
Background: CD5, also known as Leu-1, is a type I transmembrane protein belonging to the scavenger receptor cysteine-rich (SRCR) superfamily. It is expressed on thymocytes, T cells and the B1a subpopulation of B cells. CD5 binds the C-type lectin, CD72, and modulates signaling through the antigen receptors on T and B cells. CD5 has been shown to provide either positive or negative co-stimulatory signals depending on cell type to regulate immune responses.
Immunogen: Recombinant Human CD5 / Cluster of Differentiation 5 Protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:1000;
Calculated MW: 55 kDa
Observed MW: 58 kDa
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