Recombinant Phospho-PLCγ1 (Tyr783) Monoclonal Antibody

Recombinant Phospho-PLCγ1 (Tyr783) Monoclonal Antibody
Artikelnummer
ELSAN300148L-100
Verpackungseinheit
100μL
Hersteller
Elabscience Biotechnology

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Target Synonym: PLCG;phospholipase C gamma;NCKAP;PLCgamma;PLC;PLCG1;NCKAP3;PLC-II;PLC1;PLC148;PLCgamma1;phospholipase C gamma 1;NCKAP3;phospholipase C gamma 1;PLC1;PLC148;PLCgamma1;PLC-II

Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 2 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen: A synthetic phosphopeptide corresponding to residues around Tyr783 of the Human PLCγ1

Buffer: 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL protein protectant, 50% glycerol, pH 7.5

Dilution: WB 1:500-1:5000;

Calculated MW: 150 kDa

Observed MW: 148 kDa
Mehr Informationen
Artikelnummer ELSAN300148L-100
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer AN300148L-100
Verpackungseinheit 100μL
Mengeneinheit STK
Reaktivität Human
Klonalität Recombinant
Methode Western Blotting
Isotyp IgG
Wirt Rabbit
Konjugat Unconjugated
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