Target Synonym: GLP;GCG;GLP-1;GLP1;GLP2;GRPP;glucagon;Glicentin-Related Polypeptide;GLP-1(7-36);GLP-1(7-37);Glucagon-like peptide 1;Glucagon-Like Peptide 2;Incretin hormone;Pro-glucagon;Glicentin;Oxyntomodulin;OXM;OXY;GLP-2;GLP 1;GCG;Glucagon
Background: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Immunogen: A synthetic peptide corresponding to the Human GCG/Glucagon
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:100-1:500
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