Target Synonym: UNQ;PRO;IL1F;IL1H;IL-1-related protein;Interleukin-1 homolog;IL-1F;IL-1H;IL1RP;IL-1RP;IL36G;IL-1F9;IL-1H1;IL-1RP2;IL1E;IL1F9;IL1H1;IL1RP2;IL-1 epsilon;IL-1-related protein 2;Interleukin-1 homolog 1;Interleukin-36 gamma;UNQ2456;PRO5737
Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. The activity of this cytokine is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). Interferon-gamma, tumor necrosis factor-alpha and interleukin 1, beta (IL1B) are reported to stimulate the expression of this cytokine in keratinocytes. The expression of this cytokine in keratinocytes can also be induced by a contact hypersensitivity reaction or herpes simplex virus infection. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen: Recombinant Human IL36G/IL1F9 Protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: IHC-P 1:10000-1:20000