Target Synonym: IRF;IRF3;entrez:3661;IIAE7;IRF-3;IRF-3
Background: This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer: PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Immunogen: Recombinant Human IRF3 protein
Dilution: IHC 1:200-1:1000;WB 1:500-1:2000
Calculated MW: 47 kDa
Observed MW: 55 kDa