REGN5093-M114

Product Description: REGN5093-M114 is a bispecific antibody-drug conjugate (ADC) that targets two epitopes of the MET receptor tyrosine kinase inhibits the proliferation of NSCLC cells, exhibits antitumor efficacy in mouse models. REGN5093-M114 is composed of the human monoclonal anti-MET antibody Davutamig (HY-P990073) and the tubulin-inhibiting linker-payload (HY-148528)[1].

Formula: N/A

References: [1]Dardare J, et al., REGN5093-M114: can an antibody-drug conjugate overcome the challenge of resistance to epidermal growth factor receptor and mesenchymal epithelial transition tyrosine kinase inhibitors in non-small cell lung cancer? Transl Lung Cancer Res. 2024 Aug 31;13(8):2082-2086.

Molecular Weight: N/A

Research Area: Cancer

Target: Antibody-Drug Conjugates (ADCs);c-Met/HGFR;Microtubule/Tubulin

• Artikelnummer: MEXHY-171191-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-171191-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK