Specificity: Recognizes the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.
Antibody Modification: RPE
Presentation: PBS, 0.1% sodium azide, stabilizing agent.
Gene: Human Kappa Light Chain
Description: Human Kappa Light Chain antibody LS-C56031 is an RPE-conjugated goat polyclonal antibody. Validated for Flow.
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Synonyms: , IgK, Ig Kappa
Recommended Storage: Store at 4°C. Do not freeze. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
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