Product Description: 13,14-Dihydro PGE1-d4 (13,14-Dihydroprostaglandin E1-d4) is deuterium labeled 13,14-Dihydro PGE1. 13,14-Dihydro PGE1 is a metabolite of PGE1 (Prostaglandin E1) which inhibits the ADP-induced platelet aggregation (ID50 = 10.8 ng/mL platelet rich plasma)[1][2].
Formula: C20H32D4O5
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Katzenschlager R, et al. Synergism between PGE1-metabolites(13,14-dihydro-prostaglandin E1, 15-keto prostaglandin E1, 15-keto-13,14-dihydro-prostaglandin E1) and nitric oxide (NO) on platelet aggregation. Prostaglandins Leukot Essent Fatty Acids. 1992 Mar;45(3):207-10.
CAS Number: 2705226-66-8
Molecular Weight: 360.52
Research Area: Metabolic Disease
Target: Endogenous Metabolite;Isotope-Labeled Compounds
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