4-Phenylbutyric acid-d5, CAS 64138-52-9

4-Phenylbutyric acid-d5, CAS 64138-52-9
Artikelnummer
MEXHY-A0281S2-1
Verpackungseinheit
1 mg
Hersteller
MedChemExpress

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Product Description: 4-Phenylbutyric acid-d5 is the deuterium labeled 4-Phenylbutyric acid[1]. 4-Phenylbutyric acid (4-PBA) is an inhibitor of HDAC and endoplasmic reticulum (ER) stress, used in cancer and infection research[2][3][4].

Applications: COVID-19-anti-virus

Formula: C10H7D5O2

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Chang TH, et al. Enhanced growth inhibition by combination differentiation therapy with ligands of peroxisome proliferator-activated receptor-gamma and inhibitors of histone deacetylase in adenocarcinoma of the lung. Clin Cancer Res. 2002 Apr;8(4):1206-12./[3]Frouco G, et, al. Sodium phenylbutyrate abrogates African swine fever virus replication by disrupting the virus-induced hypoacetylation status of histone H3K9/K14. Virus Res. 2017 Oct 15;242:24-29./[4]Park HJ, et al. 4-Phenylbutyric acid protects against lipopolysaccharide-induced bone loss by modulating autophagy in osteoclasts. Biochem Pharmacol. 2018 May;151:9-17.

CAS Number: 64138-52-9

Molecular Weight: 169.23

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: HDAC;Virus Protease
Mehr Informationen
Artikelnummer MEXHY-A0281S2-1
Hersteller MedChemExpress
Hersteller Artikelnummer HY-A0281S2-1
Verpackungseinheit 1 mg
Mengeneinheit STK
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