ART899, CAS 2607139-85-3

Product Description: ART899 is a highly specific allosteric inhibitor of the Polθ DNA polymerase domain. ART899 can effectively enhance the radiosensitivity of tumor cells, shows good tolerance when combined with fractionated radiation, and significantly reduces tumor growth compared to radiation alone[1].

Formula: C19H13D3ClF4N3O4

References: [1]Gonzalo Rodriguez-Berriguete, et al. Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models. Clin Cancer Res. 2023 Apr 14;29(8):1631-1642.

CAS Number: 2607139-85-3

Molecular Weight: 464.81

Research Area: Cancer

Target: DNA/RNA Synthesis

• Artikelnummer: MEXHY-139289S-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-139289S-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK