Product Description: Caspofungin-d4 (acetate) is the deuterium labeled Caspofungin diacetate[1]. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[2][3].
Applications: COVID-19-immunoregulation
Formula: C56H92D4N10O19
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Flattery AM, et, al. Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis. Antimicrob Agents Chemother. 2011 Jul;55(7):3491-7./[3]Mojumder DK, et, al. Evaluating retinal toxicity of intravitreal caspofungin in the mouse eye. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5796-803.
Molecular Weight: 1217.44
Compound Purity: 95.4
Research Area: Infection
Solubility: 10 mM in DMSO
Target: Antibiotic;Bacterial;Fungal
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