Product Description: Exatecan-d5 mesylate is deuterium labeled Exatecan mesylate (HY-13631A). Exatecan mesylate is a DNA topoisomerase I inhibitor, with an IC50 of 0.975 μg/mL[1].
Applications: Cancer-programmed cell death
Formula: C25H21D5FN3O7S
References: [1]Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.
CAS Number: 2819276-88-3
Molecular Weight: 536.58
Compound Purity: 99.83
Research Area: Cancer
Solubility: DMSO : 11.76mg/mL (ultrasonic)/H2O : 1mg/mL (ultrasonic;warming;heat to 80°C)
Target: ADC Cytotoxin;Isotope-Labeled Compounds;Topoisomerase