Product Description: Histamine-d4 (Ergamine-d4) is deuterium labeled Histamine. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter.
Applications: Metabolism-protein/nucleotide metabolism
Formula: C5H5D4N3
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Rizell M, Naredi P, Lindnér P, Hellstrand K, Sarno M, Jansson PA. Histamine pharmacokinetics in tumor and host tissues after bolus-dose administration in the rat. Life Sci. 2002 Jan 11;70(8):969-76. /[3]Okabe S, et al. Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. Am J Dig Dis. 1977 Aug;22(8):677-84.
CAS Number: 751471-48-4
Molecular Weight: 115.17
Research Area: Neurological Disease;Endocrinology;Cancer
Target: Endogenous Metabolite;Histamine Receptor;Isotope-Labeled Compounds