Product Description: N-Acetyl-L-aspartic acid-d3 is the deuterium labeled N-Acetyl-L-aspartic acid (HY-113524). N-Acetyl-L-aspartic acid is a derivative of Aspartic acid (HY-N0666) and endogenous compound. N-Acetyl-L-aspartic acid acts as an acetyl donor. N-Acetyl-L-aspartic acid is involved in brain metabolism. N-Acetyl-L-aspartic acid is used in the research of neurodegenerative diseases (such as Canavan disease)[1][2][3][4][5][6].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C6H6D3NO5
References: [1]Birken DL, et al. N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain. Neurosci Biobehav Rev. 1989 Spring;13(1):23-31./[2]Buniatian HC, et al. The participation of N-acetyl-L-aspartic acid in brain metabolism. J Neurochem. 1965 Aug;12(8):695-703./[3]Sreekumar A, et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4./[4]Karaman S, et al. Subchronic oral toxicity assessment of N-acetyl-L-aspartic acid in rats. Food Chem Toxicol. 2011 Jan;49(1):155-65. /[5]Karaman S, et al. Two-generation reproductive and developmental toxicity assessment of dietary N-acetyl-L-aspartic acid in rats. Food Chem Toxicol. 2011 Dec;49(12):3192-205./[6]Delaney B, et al. Acute and repeated dose oral toxicity of N-acetyl-l-aspartic acid in Sprague-Dawley rats. Food Chem Toxicol. 2008 Jun;46(6):2023-34.
CAS Number: 284665-15-2
Molecular Weight: 178.16
Compound Purity: 99.77
Research Area: Neurological Disease
Solubility: H2O : 62.5 mg/mL (ultrasonic;warming)
Target: Endogenous Metabolite;Isotope-Labeled Compounds
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