N-Desmethyl dosimertinib-d5, CAS 2719691-00-4

Product Description: N-Desmethyl dosimertinib-d5 is the deuterium labeled Dosimertinib (HY-142283). Dosimertinib is a highly potent, selective, and orally active deuterated EGFR inhibiotor. Dosimertinib can be used for the research of non-small-cell lung cancer[1][2].

Applications: Cancer-Kinase/protease

Formula: C27H26D5N7O2

References: [1]Yonggang Meng, et al. Discovery of Dosimertinib, a Highly Potent, Selective, and Orally Efficacious Deuterated EGFR Targeting Clinical Candidate for the Treatment of Non-Small-Cell Lung Cancer. J Med Chem. 2021 Jan 28;64(2):925-937. /[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

CAS Number: 2719691-00-4

Molecular Weight: 490.61

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: EGFR

• Artikelnummer: MEXHY-142283BS-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-142283BS-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK