N-Desmethyl zopiclone-d8, CAS 1189805-43-3

N-Desmethyl zopiclone-d8, CAS 1189805-43-3
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MEXHY-U00199S-0
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Product Description: N-Desmethyl zopiclone-d8 is deuterium labeled Norzopiclone. Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.

Applications: Neuroscience-Neuromodulation

Formula: C16H7D8ClN6O3

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Sha Y, et al. Synthesis of RP 48497, an impurity of eszopiclone. Molecules. 2008 Aug 22;13(8):1817-21./[3]Thomas P. Jerussi, et al. Methods of making and using N-desmethylzopiclone. US 6339086 B1./[4]Tornio A, et al. The CYP2C8 inhibitor gemfibrozil does not increase the plasma concentrations of zopiclone. Eur J Clin Pharmacol. 2006 Aug;62(8):645-51.

CAS Number: 1189805-43-3

Molecular Weight: 382.83

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Drug Metabolite;Isotope-Labeled Compounds
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Artikelnummer MEXHY-U00199S-0
Hersteller MedChemExpress
Hersteller Artikelnummer HY-U00199S-0
Verpackungseinheit Get quote
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