Product Description: [Pyr1]-Apelin-13, Pro(13C5,15N) (TFA) is the 13C and 15N labeled isotope of [Pyr1]-Apelin-13(HY-P1033).[Pyr1]-Apelin-13 is a potent and selective endogenous apelin receptor agonist[1].
Applications: Neuroscience-Neuromodulation
Formula: C64 13C5H108N21 15NO16S.xC2HF3O2
References: [1]Hajimashhadi Z, et al. Chronic administration of [Pyr1] apelin-13 attenuates neuropathic pain after compression spinal cord injury in rats. Neuropeptides. 2017 Feb;61:15-22./[2]Serpooshan V, et al. [Pyr1]-Apelin-13 delivery via nano-liposomal encapsulation attenuates pressure overload-induced cardiac dysfunction. Biomaterials. 2015 Jan;37:289-98./[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
Molecular Weight: 1539.76 (free acid)
Compound Purity: 99.85
Research Area: Cardiovascular Disease
Solubility: H2O : 100 mg/mL (ultrasonic)
Target: Isotope-Labeled Compounds
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