Quabodepistat-d7

Product Description: Quabodepistat-d7 (OPC-167832-d7) is deuterium labeled Quabodepistat. Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with?an IC50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis?caused by?Mycobacterium tuberculosis[1].

Applications: COVID-19-immunoregulation

Formula: C21H13D7ClF3N2O4

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Norimitsu Hariguchi, et al. OPC-167832, a Novel Carbostyril Derivative with Potent Antituberculosis Activity as a DprE1 Inhibitor.Antimicrob Agents Chemother. 2020 May 21;64(6):e02020-19.

Molecular Weight: 463.89

Research Area: Infection;Inflammation/Immunology

Target: Bacterial;Isotope-Labeled Compounds

• Artikelnummer: MEXHY-134940S-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-134940S-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK