(Rac)-Hesperetin-13C,d3, CAS 2750534-85-9

(Rac)-Hesperetin-13C,d3, CAS 2750534-85-9
Artikelnummer
MEXHY-N0168AS1-500UG
Verpackungseinheit
500 μg
Hersteller
MedChemExpress

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Product Description: (Rac)-Hesperetin-13C,d3 is the 13C- and deuterium labeled (Rac)-Hesperetin. (Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation.

Applications: Cancer-Kinase/protease

Formula: C15 13CH11D3O6

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223./[2]Arya A, et al. Bioflavonoid hesperetin overcome bicalutamide induced toxicity by co-delivery in novel SNEDDS formulations: Optimization, in vivo evaluation and uptake mechanism. Mater Sci Eng C Mater Biol Appl. 2017 Feb 1;71:954-964/[3]Li Q, et al. Hesperetin Induces Apoptosis in Human Glioblastoma Cells via p38 MAPK Activation. Nutr Cancer. 2019 Jul 11:1-8./[4]Liu D, et al. Inhibitory Effect of Hesperetin and Naringenin on Human UDP-Glucuronosyltransferase Enzymes: Implications for Herb-Drug Interactions. Biol Pharm Bull. 2016;39(12):2052-2059./[5]Shagirtha K, et al. Neuroprotective efficacy of hesperetin against cadmium induced oxidative stress in the brain of rats. Toxicol Ind Health. 2016 Nov 1. pii: 0748233716665301

CAS Number: 2750534-85-9

Molecular Weight: 306.29

Compound Purity: 99.3

Research Area: Cancer; Neurological Disease

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;Isotope-Labeled Compounds;p38 MAPK
Mehr Informationen
Artikelnummer MEXHY-N0168AS1-500UG
Hersteller MedChemExpress
Hersteller Artikelnummer HY-N0168AS1-500UG
Verpackungseinheit 500 μg
Mengeneinheit STK
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