Product Description: Resiquimod-d5 is deuterium labeled Resiquimod. Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α[1][2].
Applications: COVID-19-anti-virus
Formula: C17H17D5N4O2
References: [1]Sachan S, et al. Adjuvant potential of resiquimod with inactivated Newcastle disease vaccine and its mechanism of action in chicken. Vaccine. 2015 Aug 26;33(36):4526-32./[2]Zhou ZX, et al. Immune effects of R848: evidences that suggest an essential role of TLR7/8-induced, Myd88- and NF-κB-dependent signaling in the antiviral immunity of Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2015 Mar;49(1):113-20.
CAS Number: 2252319-44-9
Molecular Weight: 319.41
Compound Purity: 99.84
Research Area: Infection; Inflammation/Immunology
Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : 0.1mg/mL (ultrasonic)
Target: HCV;Isotope-Labeled Compounds;Toll-like Receptor (TLR)