Simvastatin-d3, CAS 1002347-61-6

Product Description: Simvastatin-d3 is the deuterium labeled Simvastatin[1]. Simvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C25H35D3O5

References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216./[2]Slater, E.E., et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs, 1988. 36 Suppl 3: p. 72-82.

CAS Number: 1002347-61-6

Molecular Weight: 421.58

Research Area: Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Apoptosis;Autophagy;Ferroptosis;HMG-CoA Reductase (HMGCR);Mitophagy

• Artikelnummer: MEXHY-17502S1-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-17502S1-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK