AZD 4604, CAS 2241039-81-4

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-[3-[5-fluoro-2-[[2-fluoro-3-(methylsulfonyl)phenyl]amino]-4-pyrimidinyl]-1H-indol-7-yl]-aR-(methoxymethyl)-4-methyl-1-piperazineacetamide

Purity: ≥98%

Formula Markup: C28H31F2N7O4S

Formula Weight: 599.7

CAS Number: 2241039-81-4

Notes: A JAK1 inhibitor (IC50 = 0.54 nM); selective for JAK1 over JAK2 and JAK3 (IC50s = 686 and >10,000 nM, respectively), as well as TYK2 (IC50 = 657 nM); inhibits IL-4- or IL-13-induced phosphorylation of STAT6 in U937 cells (IC50s = 24 and 34 nM, respectively); reduces lung STAT3 and STAT5 phosphorylation in a rat model of ovalbumin-induced asthma at 1 mg/kg; inhibits lung eosinophilia and reduces the late asthmatic response in the same model

• Artikelnummer: CAY39890-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 39890-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK