BIRT 377, CAS 213211-10-0

Shelf life (days): 1460

Info: A negative allosteric modulator of LFA-1; selectively inhibits the LFA-1-ICAM-1 interaction over the ITGAM/CD11b-ICAM-1 interaction in cell-free assays at 225 µM; inhibits LFA-1-mediated binding of SKW-3 cells to ICAM-1 (IC50 = 2.6 µM); reduces SEB-induced increases in plasma IL-2 levels in mice at 25 and 50 mg/kg; intrathecal administration reduces allodynia in PAE rats in a model of minor chronic constriction injury-induced sciatic neuropathy at 500 ng/animal

Formulation: A solid

Formal Name: (5R)-5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethyl-2,4-imidazolidinedione

Purity: ≥98%

Formula Markup: C18H15BrCl2N2O2

Formula Weight: 442.134

CAS Number: 213211-10-0

• Artikelnummer: CAY43171-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 43171-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK