Camostat mesylate, CAS 59721-29-8

Serine protease inhibitor
Artikelnummer
STRSIH-585-50MG
Verpackungseinheit
50 mg
Hersteller
Stressmarq Biosciences

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Product Type: Inhibitor

CAS No.: 59721-29-8

MolecularFormula: C20H22N4O5·CH3SO3H

Molecular Weight: 494,5

Source: Synthetic

Purity: >98% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (50 mg/mL) or Water (50mg/mL)

Appearance: Off-white powder

PubChem CID: 5284360

Scientific Background: Camostat mesylate is an orally active protease inhibitor. It inhibits the serine protease TMPRSS2 and partially blocks entry of SARS-Cov-2 (Covid-19) into lung cells and Human coronavirus NL63 into HeLa cells. It has also been used in some cancer treatments, against viral infections, and for inhibiting fibrosis in liver, kidney disease and pancreatitis.

References: 1. Okuno M., et al. (2002). Front Biosci. 7 (4): d204-218. 2. Hsieh H. P., Hsu, J. T. (2007). Current Pharmaceutical Design. 13 (34): 3531–3542. 3. Kitamura K., Tomita K. (2012). Clinical and Experimental Nephrology. 16 (1): 44–48. 4. Kawase M., Shirato K., van der Hoek L., Taguchi F., Matsuyama S. (2012) J Virol. 86(12): 6537-6545. 5.. Hoffman M., et al. (2020) Cell: https://doi.org/10.1016/j.cell.2020.02.052

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Mehr Informationen
Artikelnummer STRSIH-585-50MG
Hersteller Stressmarq Biosciences
Hersteller Artikelnummer SIH-585-50MG
Verpackungseinheit 50 mg
Mengeneinheit STK
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