Product Description: closed-HMRG is HMRG with closed spirocyclic structure. Ac-HMRG, an acetylated derivative of Hydroxymethyl rhodamine green, exists as a closed spirocyclic structure in aqueous solution at physiological pH, whereas HMRG itself takes an open nonspirocyclic structure. Ac-HMRG is colorless and nonfluorescent and HMRG is strongly fluorescent[1].
Formula: C20H16N2O2
References: [1]Masayo Sakabe, et al. Rational design of highly sensitive fluorescence probes for protease and glycosidase based on precisely controlled spirocyclization. J Am Chem Soc. 2013 Jan 9;135(1):409-14.
CAS Number: 7449-51-6
Molecular Weight: 316.35
Target: Fluorescent Dye