iso-ADP ribose, CAS 15720-01-1

Product Description: iso-ADP ribose (isoADPr) is a ligand used for protein nucleic acid modification. iso-ADP ribose is a structure comprising parts of two consecutive ADP-ribosyl units within the PAR chain. iso-ADP ribose is the small-molecule ligand for RING finger protein 146 (RNF146) WWE. A single iso-ADP ribose molecule triggers the activation of RNF146 by interacting with the basic Lys61 residue in the RING domain[1][2].

Formula: C15H23N5O14P2

References: [1]Kewen Peng, et al. Iso-ADP-Ribose Fluorescence Polarization Probe for the Screening of RNF146 WWE Domain Inhibitors. ACS Chem Biol. 2024 Feb 16;19(2):300-307./[2]Federico Teloni, et al. Readers of poly(ADP-ribose): designed to be fit for purpose. Nucleic Acids Res. 2016 Feb 18;44(3):993-1006.

CAS Number: 15720-01-1

Molecular Weight: 559.32

Research Area: Others

Target: Fluorescent Dye

• Artikelnummer: MEXHY-135782-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-135782-0
• Verpackungseinheit: Get quote
• Mengeneinheit: STK