Product Description: PFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation[1].
Formula: C24H27N5O
References: [1]Owens DDG, et al., A chemical probe to modulate human GID4 Pro/N-degron interactions. Nat Chem Biol. 2024 May 21.
CAS Number: 2910938-58-6
Molecular Weight: 401.50
Research Area: Others
Target: E1/E2/E3 Enzyme